C57BL/6N-Magtm1(MAG)Bcgen/Bcgen • 111033
| Product name | B-hMAG mice |
|---|---|
| Catalog number | 111033 |
| Strain name | C57BL/6N-Magtm1(MAG)Bcgen/Bcgen |
| Strain background | C57BL/6N |
| NCBI gene ID | 4099 (Human) |
| Aliases | GMA; S-MAG; SPG75; SIGLEC4; SIGLEC4A; SIGLEC-4A |
Strain specific analysis of MAG gene expression in wild-type mice and B-hMAG mice by RT-PCR. Mouse Mag mRNA was detectable in brain of wild-type mice (+/+). Human MAG mRNA was detectable only in homozygous B-hMAG mice (H/H) but not in wild-type mice.
Strain specific MAG expression analysis in homozygous B-hMAG mice by ELISA. Brain was collected from wild-type mice (+/+) and homozygous B-hMAG mice (H/H), and analyzed by ELISA with species-specific MAG ELISA kit. MAG was detectable in wild-type mice and homozygous B-hMAG mice, as the antibody is crossly reactive with MAG in human and mice.