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    B-hCD98HC mice(C)

    BALB/cCrSlcNifdc-Slc3a2tm1(SLC3A2)Bcgen/Bcgen • 113488

    B-hCD98HC mice(C)

    Product nameB-hCD98HC mice(C)
    Catalog number113488
    Strain nameBALB/cCrSlcNifdc-Slc3a2tm1(SLC3A2)Bcgen/Bcgen
    Strain backgroundBALB/cCrSlcNifdc
    NCBI gene ID6520 (Human)
    Aliases4F2; CD98; MDU1; 4F2HC; 4T2HC; NACAE; CD98HC

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    • Targeting strategy
    • Phenotypic analysis

    海报

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      发表文章

        Targeting Strategy

        The extracellular domain of the mouse Cd98 gene (exons 2–10) is replaced with human CD98 exons 4–12.

        Protein expression analysis

        Western blot analysis of CD98HC protein expression in homozygous B-hCD98HC mice(C). Various tissue lysates were collected from wild-type BALB/c mice (+/+) and homozygous B-hCD98HC mice(C) (H/H), and then analyzed by western blot with species-specific anti-human CD98 antibody (Abcam, ab307587). 40 μg total proteins were loaded for western blotting analysis. Human CD98 was detected in spleen, lung, kidney, stomach, cortex, hippocampus, cerebellum, colon, muscle and testis from homozygous B-hCD98HC mice(C) but not in heart and liver.

        * When publishing results obtained using this animal model, please acknowledge the source as follows: The animal model [B-hCD98HC mice(C)] (Cat# 113488) was purchased from Biocytogen.